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2019 New and Views Assignment Articles

Topic 1

Nat Commun. 2019 Mar 5;10(1):1050. doi: 10.1038/s41467-019-08982-9.

Loss of a proteostatic checkpoint in intestinal stem cells contributes to age-related epithelial dysfunction.

Topic 2

J Cell Sci. 2016 Mar 1;129(5):994-1002. doi: 10.1242/jcs.176792. Epub 2016 Jan 26.

Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.

Topic 3

Nat Chem Biol. 2017 Dec;13(12):1239-1244. doi: 10.1038/nchembio.2493. Epub 2017 Oct 9.

Stendomycin selectively inhibits TIM23-dependent mitochondrialprotein import.

Topic 4

Mol Cell. 2019 Mar 6. pii: S1097-2765(19)30100-5. doi: 10.1016/j.molcel.2019.02.010. [Epub ahead of print]

Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.

Topic 5

Nat Commun. 2016 Nov 24;7:13565. doi: 10.1038/ncomms13565.

The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities.

Topic 6

EMBO J. 2018 Sep 3;37(17). pii: e99238. doi: 10.15252/embj.201899238. Epub 2018 Jul 26.

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis.